ea0035p571 | Endocrine tumours and neoplasia | ECE2014
Vaz Catia V
, Alves Marco G
, Marques Ricardo
, Moreira Paula I
, Oliveira Pedro F
, Cavaco Jose E
, Maia Claudio J
, Socorro Silvia
Prostate cancer (PCa) is an endocrine tumor that presents distinct metabolic features associated with neoplastic development, namely in the transition from the androgen-dependent to the androgen-independent phenotype that characterizes advanced stages of prostate cancer. Recently, we have found that LNCaP (androgen-responsive) and PC3 (androgen-nonresponsive) PCa cells present distinct glycolytic metabolism profiles in consequence of altered gene expression and/or activity of ...